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Tramadol is used to relieve moderate to severe pain. It also may be used to treat pain as a result of surgery and chronic conditions such as cancer. Tramadol comes as a tablet to be taken orally. It is usually taken every 4-6 hours as needed or prescribed. Follow the directions on the prescription label carefully, and ask your pharmacist to explain anything you do not understand. It may be taken with or without food. Do not take a double dose to make up for a missed one. Take any missed dose as soon as you remember to. If it is almost time for the next dose, skip the missed dose and continue your regular schedule.